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Study identifier: NCT07354724 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

Condition: Late-onset Pompe Disease  ·  Sponsor: Denali Therapeutics Inc.

PhasePhase 1
Planned participants32
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a Phase 1, multicenter, open-label study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of DNL952 in adult participants with late-onset Pompe disease. The principal aim of this study is to obtain safety and tolerability data across varous dose levels of DNL952 in participants with late-onset Pompe disease (LOPD).

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (3)

University of California-IrvineIrvine, California, United StatesRecruiting
Duke University School of Medicine - Early Phase Research UnitDurham, North Carolina, United StatesRecruiting
The Lysosomal & Rare Disorders Research & Treatment CenterFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07354724