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Study identifier: NCT07354074 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

Condition: Chronic Myelogenous Leukemia · Leukemia, Myelogenous, Chronic, Philadelphia Chromosome Positive  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 2
Planned participants50
Who can joinAll sexes, 1 Year to 18 Years
Healthy volunteersNo

About this study

The aim of this study is to support development of asciminib in the pediatric population (1 to \< 18 years) with Ph+ CML-CP. The study will evaluate the efficacy and safety of asciminib in pediatric formulation (weigh-based dose, fed state) or adult formulation (fasted) in newly diagnosed and resistant or intolerant Ph+ CML-CP with or without T315I mutation.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (24)

Rutgers Cancer Institute of New JerseyNew Brunswick, New Jersey, United StatesRecruiting
Columbia University Medical Center New York PresbyterianNew York, New York, United StatesRecruiting
Seattle Childrens HospitalSeattle, Washington, United StatesRecruiting
Novartis Investigative SiteBrisbane, Queensland, AustraliaRecruiting
Novartis Investigative SiteNorth Adelaide, South Australia, AustraliaRecruiting
Novartis Investigative SiteEdmonton, Alberta, CanadaRecruiting
Novartis Investigative SiteMontreal, Quebec, CanadaRecruiting
Novartis Investigative SiteZhengzhou, Henan, ChinaRecruiting
Novartis Investigative SiteTianjin, ChinaRecruiting
Novartis Investigative SiteMarseille, FranceRecruiting
Novartis Investigative SiteParis, FranceRecruiting
Novartis Investigative SitePoitiers, FranceRecruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07354074