Condition: Alzheimer Disease · Biomarker in Early Diagnosis · Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Alzheimer's disease is the most common memory loss disease among the elderly. This disease affects the patient's memory, language, attention, and behavioral abilities. Current research has found that in the early stages of the disease, synaptic connections between brain nerve cells become abnormal, but the specific cause is still unclear. Investigators' previous research discovered that in the brains of diseased mice, certain special substances (the miR 342 5p/AnkG-mediated pathway) might be related to this abnormality, and these substances can be detected in both blood and cerebrospinal fluid. Therefore, investigators want to further explore the specific mechanisms of abnormal nerve cell connections, seek biomarkers for early detection of the disease, and provide new ideas for early diagnosis in the future.
This description comes directly from the study's public registry record.
Xu-hua Xu · +8613705790560 · fupinglangying@zju.edu.cn
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| The Fourth Affiliated Hospital of Zhejiang University School of Medicine | Yiwu, Zhejiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07353502