Condition: Colo-rectal Cancer (dMMR/MSI-H CRC) · Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences
This study is a prospective, observational, real-world investigation. This study will evaluate the efficacy and safety of tislelizumab monotherapy before surgery in patients with mismatch repair deficient or microsatellite instability high (dMMR/MSI-H) locally advanced colorectal cancer. All patients will receive three cycles of tislelizumab neoadjuvant therapy followed by curative surgery. Postoperatively, based on surgical pathology, patients will receive adjuvant therapy with a regimen selected by the investigator or adopt a watch-and-wait strategy. The investigators will conduct a 5-year prospective follow-up. The investigators plan to enroll approximately 30 subjects.
This description comes directly from the study's public registry record.
Lin Yang · 8601087788145 · linyangcicams@126.com
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| Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Beijing, Undefined, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07352280