Condition: Post-Acne Atrophic Scars · Carbon Dioxide Lasers · Platelet-Rich Plasma · Sponsor: Gujranwala medical college District Headquarters Hospital, Gujranwala
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone. Seventy adults aged 18-40 years will be recruited from the Dermatology Department of Gujranwala Medical College Teaching Hospital. Participants will be randomly assigned to receive either fractional CO₂ laser combined with topical PRP or fractional CO₂ laser alone, with three treatment sessions delivered four weeks apart. The primary outcome is the change in acne scar severity measured using the Goodman and Baron Quantitative Acne Scar Scale. Secondary outcomes include redness, edema, pain scores, and patient satisfaction assessed using Likert and numeric rating scales. The study is single-blinded, with patients unaware of treatment allocation. PRP will be prepared using a standardized double-spin centrifugation process. Data will be analyzed using appropriate statistical tests with a significance level of p \< 0.05. The study aims to determine whether PRP enhances laser efficacy, reduces side effects, and improves patient-reported outcomes.
This description comes directly from the study's public registry record.
YASAAN SAAQIB, MBBS · 0923234525277 · saani1992222@gmail.com
Nabeela Shahzadi · +92 331 4218784 · nabeela.pk82@gmail.com
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| Destrict Head Quarter Hospital, Gujranwala | Gujranwala, Punjab Province, Pakistan | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07352215