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Study identifier: NCT07350252 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty

Condition: Osteo Arthritis of the Knee  ·  Sponsor: Region Skane

PhasePhase 4
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this clinical randomized trial is to compare local infiltration analgesia (LIA) alone versus the combination of LIA with saphenous nerve (SN) block, block of the nerve to vastus medialis (NVM), and anterior femoral cutaneous nerve (AFCN) block in participants undergoing total knee arthroplasty (TKA). The primary outcome is pain intensity, measured using the Numerical Rating Scale (NRS) at multiple time points after surgery. Secondary outcomes include opioid consumption, time to mobilization, postoperative nausea and vomiting, length of hospital stay, neurological complications and differences in opioid consumption and NRS pain scores between general and spinal anesthesia.

This description comes directly from the study's public registry record.

Talk to the study team

Fredrik Fellert, MD  ·  +46736552249  ·  fredrik.fellert@med.lu.se

Andreas Ekman, MD, PhD  ·  +46702542552  ·  andreas.ekman@med.lu.se

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Anaesthesiology, Trelleborg HospitalTrelleborg, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07350252