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Study identifier: NCT07349095 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

AI-Assisted Colorimetric Diagnosis of Peri-Implant Mucosal Erythema

Condition: Peri-implant Mucositis  ·  Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

1. Background and Rationale The visual diagnosis of peri-implant mucosal erythema (redness), a key sign of inflammation, is highly subjective and varies significantly among clinicians, leading to inconsistencies in early detection and monitoring of peri-implant diseases. There is a critical need for an objective, quantitative, and reliable tool to standardize this assessment. Recent advances in artificial intelligence (AI) and colorimetric analysis of digital intraoral scans offer a promising solution to this clinical challenge. 2. Primary Objectives This diagnostic study aims to: Develop and validate a core colorimetric index that objectively quantifies mucosal erythema from digital intraoral scan data. Develop and validate an AI model that automatically calculates this index and provides a binary diagnosis (erythema present/absent) at the image level. Develop and validate a second AI model for precise localization (object detection) of erythematous regions on standard clinical software screenshots. Evaluate the clinical utility of the AI system by assessing its impact on the diagnostic accuracy, consistency, and confidence of clinicians with varying experience levels. 3. Study Design This is a multiphase diagnostic accuracy study conducted at a single academic center. It comprises three sequential phases with independent validation: Phase 1 (Development \& Internal Validation): Analysis of intraoral scans to derive the color index and train the A…

This description comes directly from the study's public registry record.

Talk to the study team

Junyu Shi, Professor  ·  021 5331 4050  ·  sakyamuni_jin@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Oral Maxillofacial Implantology Shanghai Ninth People's HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07349095