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Study identifier: NCT07347938 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 4 Study to Evaluate the Effectiveness and Safety of Siltartoxatug Injection for Tetanus Prophylaxis Following Injury

Condition: Tetanus  ·  Sponsor: Zhuhai Trinomab Pharmaceutical Co., Ltd.

PhaseN/A
Planned participants6000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Study sites were selected from hospitals across diverse regions of China. Approximately 6,000 participants who require passive immunization against tetanus due to various injuries (including those with severe wounds or heavily contaminated injuries) will be enrolled per clinical practice: Participants receiving siltartoxatug for tetanus prophylaxis and meeting eligibility criteria will be assigned to the siltartoxatug group (n=4,000); Participants receiving other passive immunizing agents (HTIG, TAT, or F(ab')₂) for tetanus prophylaxis and meeting eligibility criteria will be assigned to the control group (n=2,000), comprising approximately 1,000 HTIG recipients and 1,000 TAT/F(ab')₂ recipients. All clinical management decisions, including concomitant tetanus vaccination, will be made by investigators per standard clinical practice at each center.

This description comes directly from the study's public registry record.

Talk to the study team

Xia Qu, Master  ·  +86 0756 726399  ·  sammi.qu@trinomab.com

Xinyu Liu, Doctor  ·  +86 0756 7263999  ·  liuxinyu@trinomab.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Second Affiliated Hospital Zhejiang University School of MedicineHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07347938