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Study identifier: NCT07347600 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate the Effectiveness and Safety of Inavolisib in Participants With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer

Condition: Locally Advanced Breast Cancer · Metastatic Breast Cancer  ·  Sponsor: Hoffmann-La Roche

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main purpose of this study is to evaluate the effectiveness of inavolisib based regimen in participants with endocrine-resistant, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha gene (PIK3CA)-mutated, hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) locally advanced or metastatic breast cancer (LA/mBC), following on or after completing adjuvant endocrine therapy in routine clinical practice in China.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: ML46361 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (28)

The First Affiliated Hospital of Xiamen UniversityXiamen, Fujian, ChinaRecruiting
Gansu Provincial Maternal and Child Health Hospital (Gansu Provincial Hospital of Traditional Chinese Medicine)Lanzhou, Gansu, ChinaRecruiting
The First Hospital of Jilin UniversityChangchun, Jilin, ChinaRecruiting
Wenzhou Medical University Affiliated Second HospitalWenzhou, Zhejiang, ChinaRecruiting
Peking University First HospitalBeijing, ChinaRecruiting
Peking University Third HospitalBeijing, ChinaRecruiting
Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples HospitalChengdu, ChinaRecruiting
Chongqing Cancer HospitalChongqing, ChinaRecruiting
Sun Yat-sen Memorial HospitalGuangzhou, ChinaRecruiting
Zhujiang Hospital, Southern Medical UniversityGuangzhou, ChinaRecruiting
Guangdong Provincial Traditional Chinese Medicine HospitalGuangzhou, ChinaRecruiting
Guizhou Provincial People's HospitalGuiyang, ChinaRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07347600