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Study identifier: NCT07345325 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve Endocarditis

Condition: Infective Endocarditis  ·  Sponsor: Nantes University Hospital

PhasePhase 3
Planned participants422
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of this study is to demonstrate that a rifampin-free regimen is non-inferior to the rifampin-containing regimen in terms of all-cause mortality in staphylococcal prosthetic valve endocarditis within 6 months after randomization.

This description comes directly from the study's public registry record.

Talk to the study team

Raphaël LECOMTE, MD  ·  02 40 08 31 12  ·  raphael.lecomte@chu-nantes.fr

Always discuss trial participation with your own doctor first.

Locations (31)

CH metropole Savoie, Chambery, GHT Savoie-Belley, Site Aix les BainsAix-les-Bains, FranceRecruiting
CHU AngersAngers, FranceRecruiting
CHU BesançonBesançon, FranceNot Yet Recruiting
CHU Bordeaux, Cardiologic hospital of Haut lévêqueBordeaux, FranceRecruiting
CHU Bordeaux, Haut Lévêque Hospital, Infectious disease departmentBordeaux, FranceRecruiting
CHU BrestBrest, FranceRecruiting
AP-HP, Groupe hospitalier Henri MondorCréteil, FranceRecruiting
CHU Dijon BourgogneDijon, FranceRecruiting
CHU GrenobleGrenoble, FranceRecruiting
CHD VendéeLa Roche-sur-Yon, FranceRecruiting
CHU Lyon, La Croix-Rousse Hospital, Infective disease departmentLyon, FranceNot Yet Recruiting
CHU Lyon, Louis Pradel Hospital, Cardiology InstituteLyon, FranceNot Yet Recruiting

+ 19 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07345325