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Study identifier: NCT07343674 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PERFECT - Portuguese Evolut Registry Studying the Outcomes of Medtronic Evolut™ FX+ TAVI System by Evaluating an Optimal Care Pathway for TAVI

Condition: Severe Symptomatic Aortic Stenosis (Defined as New York Heart Association (NYHA) Class ≥ II)  ·  Sponsor: Portuguese Association of Interventional Cardiology

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this registry is to learn how the Medtronic Evolut™ FX+ transcatheter aortic valve implantation (TAVI) System performs in adults with severe, symptomatic aortic stenosis who need valve replacement. The main questions it aims to answer are: * Can using a standardized procedure for the impantation of the Medtronic Evolut™ FX+ TAVI System increase safety and efficiency? * What are the short-term (30 days) and long-term (1 year) patient outcomes, including the need for a pacemaker, complications, and valve function? Participants will undergo TAVI with the Medtronic Evolut™ FX+ TAVI System as part of their routine care. Be followed during their hospital stay, at 30 days, and at 1 year to check heart health, valve function, and recovery. 500 people at 12 hospitals in Portugal will take part in this registry.

This description comes directly from the study's public registry record.

Talk to the study team

Rui C Teles, MD, PhD  ·  (+351) 210 433 069  ·  rcteles@outlook.com

Joana D Silva, MD, PhD  ·  secretariado.apic@spc.pt

Always discuss trial participation with your own doctor first.

Locations (12)

Hospitais da Universidade de CoimbraCoimbra, Coimbra District, PortugalRecruiting
Hospital da Luz CoimbraCoimbra, Coimbra District, PortugalNot Yet Recruiting
Hospital CUF TejoLisbon, Lisbon District, PortugalRecruiting
Hospital de Santa CruzLisbon, Lisbon District, PortugalRecruiting
Hospital Lusíadas LisboaLisbon, Lisbon District, PortugalNot Yet Recruiting
Hospital da Luz LisboaLisbon, Lisbon District, PortugalNot Yet Recruiting
Hospital Santa MariaLisbon, Lisbon District, PortugalRecruiting
Hospital Santa MartaLisbon, Lisbon District, PortugalRecruiting
Hospital Dr. Nélio MendonçaFunchal, Madeira, PortugalNot Yet Recruiting
Hospital Universitário de São JoãoPorto, Porto District, PortugalRecruiting
Hospital Eduardo Santos SilvaVila Nova de Gaia, Vila Nova de Gaia, PortugalNot Yet Recruiting
Hospital do Espírito Santo de ÉvoraEvora, Évora District, PortugalNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07343674