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Study identifier: NCT07342933 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Outcomes of Children in Whom a Prenatal Exome Was Performed Based on Ultrasound Findings

Condition: Amniocentesis Affecting Fetus  ·  Sponsor: University Hospital, Strasbourg, France

PhaseN/A
Planned participants70
Who can joinAll sexes, 0 Years to 3 Years
Healthy volunteersNo

About this study

Amniocentesis is a test offered to couples based on ultrasound findings during pregnancy. Currently, genetic analysis using FISH and ACPA is routinely performed. For the past four years, additional exome sequencing has been offered after two ultrasound findings, if FISH and ACPA are negative. In this study, investigators aim to review the results of this exome sequencing analysis, examine the outcomes obtained, and study the outcomes of the children after birth. Can parents be completely reassured when the exome sequencing is negative, or does this indicate that investigators are not yet sufficiently sensitive in their genetic analysis?

This description comes directly from the study's public registry record.

Talk to the study team

Chris MINELLA, MD  ·  33 3 88 12 74 95  ·  chris.minella@chru-strasbourg.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Service de Gynécologique et d'Obstétrique - CHU de Strasbourg - FranceStrasbourg, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07342933