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Study identifier: NCT07342868 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Condition: Chronic Hepaititis B Infections  ·  Sponsor: Aligos Therapeutics

PhasePhase 1
Planned participants16
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This Phase 1 non-randomized, open-label, single-dose hepatic impairment study consists of 2 cohorts, conducted in 16 subjects, 8 subjects with moderate hepatic impairment (Cohort 1) and 8 subjects without hepatic impairment (Cohort 2), matched for age, body weight and, to the extent possible, for sex. The effect of hepatic impairment on the plasma pharmacokinetics of ALG-001075 will be assessed in subjects who have received single oral doses of pevifoscorvir sodium (ALG-000184).

This description comes directly from the study's public registry record.

Talk to the study team

Jen Rito  ·  (800) 466-6059  ·  info@aligos.com

Always discuss trial participation with your own doctor first.

Locations (1)

Orlando Clinical Research CenterOrlando, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07342868