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Study identifier: NCT07342777 Synced from ClinicalTrials.gov · July 29, 2026
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EXpain Trial - Exercise an a Non-pharmacological Pain-relieving Treatment in People With Multiple Sclerosis

Condition: Multiple Sclerosis · Chronic Pain · Neuropathic Pain  ·  Sponsor: University of Aarhus

PhaseNA
Planned participants116
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary goal of this study is to test whether 12 weeks of progressive resistance exercise is an effective non-pharmacological treatment for reducing pain in people with multiple sclerosis and chronic pain. The study will be a randomized controlled trial with multiple training sites. After baseline testing, participants will be randomly assigned to either a 12-week progressive resistance exercise intervention followed by a 12-week follow-up period or to a 24-week waitlist control group that receives usual care. It is hypothesized that people with multiple sclerosis and chronic pain who receive the intervention will experience greater reductions in pain (i.e., clinically relevant reductions) compared to the waitlist control group (primary hypothesis), and that this pain reduction will be preserved after a 12-week follow-up period (secondary hypothesis).

This description comes directly from the study's public registry record.

Talk to the study team

Rasmus C Jungersen, PhD-student  ·  +4593508304  ·  rasjun@ph.au.dk

Lars G Hvid, Associate Professor  ·  93508717  ·  lhvid@ph.au.dk

Always discuss trial participation with your own doctor first.

Locations (1)

Aarhus UniversityAarhus, Denmark, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT07342777