Condition: Allogeneic Hematopoietic Stem Cell Transplantation Recipient · Sponsor: Rigshospitalet, Denmark
Seventy-five percent of patients treated with hematopoietic stem cell transplants survive one-year post-transplantation. However, this intensive treatment is associated with prolonged hospitalizations and significant deconditioning. Pathophysiological changes in skeletal muscle mass and function have notable implications for disease progression and long-term prognosis. Patients frequently report substantial rehabilitation needs, though these needs are highly individualized and fluctuate over time, with musculoskeletal dysfunction and fa-tigue being the most common barriers to prehabilitation. Furthermore, at least 35% of cancer patients are found to have inadequate daily protein intake, which may hinder improve-ments in physical performance through prehabilitation. Several recent studies have demonstrated the safety and feasibility of exercise-based prehabilitation interventions during the pre-transplant period. However, no full-scale randomized controlled trial (RCT) has been conducted to date.
This description comes directly from the study's public registry record.
Jan Christensen, PhD · +4522479075 · jan.christensen.02@regionh.dk
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| Copenhagen University Hospital - Rigshospitalet | Copenhagen, Denmark, Denmark | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07341698