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Study identifier: NCT07340138 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis

Condition: Primary Myelofibrosis (PMF) · Post-polycythemia Vera Myelofibrosis (Post-PV MF) · Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 1
Planned participants6
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase 1b, multicenter, open-label study aims to evaluate the safety, pharmacokinetics (PK), and preliminary efficacy of pelabresib as add-on to ruxolitinib in Japanese patients with myelofibrosis (MF).

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  +81337978748  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  novartis.email@novartis.com

Always discuss trial participation with your own doctor first.

Locations (7)

Novartis Investigative SiteKamogawa, Chiba, JapanRecruiting
Novartis Investigative SiteSapporo, Hokkaido, JapanRecruiting
Novartis Investigative SiteKamakura, Kanagawa, JapanRecruiting
Novartis Investigative SiteKurashiki, Okayama-ken, JapanRecruiting
Novartis Investigative SiteBunkyo Ku, Tokyo, JapanRecruiting
Novartis Investigative SiteChūō, Yamanashi, JapanActive Not Recruiting
Novartis Investigative SiteKumamoto, JapanRecruiting

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Source record: clinicaltrials.gov/study/NCT07340138