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Study identifier: NCT07340125 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pistachio Snacking and Metabolic Flexibility

Condition: Overweight (BMI > 25) · Obese But Otherwise Healthy Participants · Overweight or Obese  ·  Sponsor: University of South Carolina

PhaseNA
Planned participants60
Who can joinAll sexes, 25 Years to 45 Years
Healthy volunteersYes

About this study

The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults. Secondary goals include evaluating effects on changes in diet quality, sleep characteristics, physical activity, and hormonal health in women. In randomized order, participants will complete four days of pistachio snacking and four days of normal dietary habits (control). For both conditions, primary outcomes of resting substrate metabolism, metabolic flexibility during exercise, and post-exercise substrate metabolism will be measured pre-post intervention via indirect calorimetry. Secondary outcome of diet quality (kcal, carb, fat, protein) will be measured pre-post intervention via diet log. Exploratory outcomes of daily physical activity (steps, intensity), nightly sleep characteristics (quantity, quality, latency, efficiency), and daytime sleepiness and hunger.

This description comes directly from the study's public registry record.

Talk to the study team

Callie Unrein, MS  ·  803-777-5478  ·  sustainlab@mailbox.sc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Public Health Research Center: Clinical Exercise Research CenterColumbia, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07340125