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Study identifier: NCT07339423 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

Condition: Obesity  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants1150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (72)

South Broward Research LLCMiramar, Florida, United StatesRecruiting
Clinical Neuroscience SolutionOrlando, Florida, United StatesRecruiting
Hope Clin Res & WellnessConyers, Georgia, United StatesRecruiting
Endeavor HealthSkokie, Illinois, United StatesRecruiting
Midwest Inst For Clin ResIndianapolis, Indiana, United StatesRecruiting
StudyMetrix Research LLCCity of Saint Peters, Missouri, United StatesRecruiting
New York Gastroenterology AssociatesNew York, New York, United StatesRecruiting
UNC Eastowne Medical OfficeChapel Hill, North Carolina, United StatesRecruiting
PharmQuest Life Sciences LLCGreensboro, North Carolina, United StatesRecruiting
Accellacare and KDCILM, LLCWilmington, North Carolina, United StatesRecruiting
UPA Ctr Weight and Eating DisPhiladelphia, Pennsylvania, United StatesRecruiting
Clinical Res CollaborativeCumberland, Rhode Island, United StatesRecruiting

+ 60 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07339423