Condition: Knee Cartilage Defects · Sponsor: Medipost, Inc.
To establish the efficacy and safety of CARTISTEM®, a combination product composed of allogeneic human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) formulated with a cross-linked sodium hyaluronate (HA) hydrogel, CARTISTEM® compared to the surgical comparator of debridement in Subjects with knee cartilage lesions and osteoarthritis. This trial is intended to provide evidence of the superiority of CARTISTEM® to reduce knee pain and improve knee function compared to debridement for Subjects with knee cartilage lesions and osteoarthritis at 2-years post-treatment. Additionally, this trial is intended to intended to explore whether CARTISTEM® may have disease-modifying effects on osteoarthritis progression through the use of semi-quantitative MRI assessment.
This description comes directly from the study's public registry record.
Adrian Orr, VP Clinical Development · 617-575-2203 · cartistem2023-01@medi-post.com
Luis Toro, Medical Monitor for IQVIA, MD
Always discuss trial participation with your own doctor first.
| Flourish Research Birmingham | Birmingham, Alabama, United States | Recruiting |
| AZ Orthopedic | Tempe, Arizona, United States | Recruiting |
| TriWest Research Associates | El Cajon, California, United States | Not Yet Recruiting |
| Horizon Clinical Research | La Mesa, California, United States | Not Yet Recruiting |
| Source Healthcare | Santa Monica, California, United States | Recruiting |
| Orthopedic Centers of Colorado | Parker, Colorado, United States | Recruiting |
| Steamboat Orthopaedic and Spine Institute | Steamboat Springs, Colorado, United States | Recruiting |
| Mayo Clinic Rochester | Rochester, Minnesota, United States | Recruiting |
| Curalta Clinical Trials | Westwood, New Jersey, United States | Recruiting |
| New York Presbyterian Queens | Flushing, New York, United States | Recruiting |
| Atrium Health Mercy | Charlotte, North Carolina, United States | Not Yet Recruiting |
| West Clinical Research | Morehead City, North Carolina, United States | Recruiting |
+ 8 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07339111