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Study identifier: NCT07335601 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH

Condition: MASH - Metabolic Dysfunction-Associated Steatohepatitis  ·  Sponsor: Madrigal Pharmaceuticals, Inc.

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

A Phase 2 double-blind, randomized, placebo-controlled study to evaluate resmetirom in 2 cohorts of subjects with moderate to advanced fibrosis, consistent with stage F2 and F3 fibrosis, who have undergone liver transplant. Cohort 1 will consist of patients who have undergone liver transplant for MASH cirrhosis who developed recurrent MASH. Cohort 2 will consist of subjects who have undergone liver transplant for indications other than MASH cirrhosis who developed de novo MASH.

This description comes directly from the study's public registry record.

Talk to the study team

David Hernandez, MD  ·  302-640-2217  ·  dhernandez@madrigalpharma.com

Always discuss trial participation with your own doctor first.

Locations (17)

University of California San DiegoLa Jolla, California, United StatesNot Yet Recruiting
University of California Los Angeles Medical CenterLos Angeles, California, United StatesNot Yet Recruiting
University of California, San FranciscoSan Francisco, California, United StatesRecruiting
University of ColoradoAurora, Colorado, United StatesNot Yet Recruiting
Medstar Georgetown University HospitalWashington D.C., District of Columbia, United StatesNot Yet Recruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
The University of Chicago MedicineChicago, Illinois, United StatesNot Yet Recruiting
Mayo ClinicRochester, Minnesota, United StatesNot Yet Recruiting
University of NebraskaOmaha, Nebraska, United StatesNot Yet Recruiting
Northwell Health Inc, Center for Liver Disease and TransplantationManhasset, New York, United StatesNot Yet Recruiting
New York Presbyterian HospitalNew York, New York, United StatesNot Yet Recruiting
Vanderbilt University Medical Center (VUMC)Nashville, Tennessee, United StatesRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07335601