Condition: Kidney Transplant · Renal Allograft Recipients · Renal Allograft · Sponsor: Tongji Hospital
This clinical study aims to investigate a new, non-invasive method for monitoring kidney function after transplantation. Currently, assessing the health of a transplanted kidney often relies on blood tests or invasive biopsies, which may not detect subtle early changes or account for each kidney's unique starting point. This research will use advanced, non-contrast Magnetic Resonance Imaging (MRI) scans to measure various aspects of kidney health, such as blood flow and oxygen levels. The study includes two main groups of participants: 1) kidney transplant donors and their matched recipients, and 2) transplant recipients whose donors are unavailable for study (e.g., deceased donors). For donor-recipient pairs, the goal is to create a personalized "baseline" for each transplanted kidney by scanning the donor before donation. This allows doctors to compare the kidney's function after transplant to its own unique starting point, potentially detecting problems much earlier. For recipients without donor data, the study will evaluate how well the MRI scans can track changes in kidney function over time on their own. Additionally, the study will analyze body composition (like fat and muscle distribution) and metabolic health to understand their relationship with transplant kidney function. We plan to enroll approximately 1000 participants across multiple hospitals. The ultimate goal is to develop a more accurate, individualized, and non-invasive tool for the early detection of tr…
This description comes directly from the study's public registry record.
Zhen Professor Li, PHD,MD · 02783663543 · zhenli@hust.edu.cn
Always discuss trial participation with your own doctor first.
| Sinopharm Dongfeng General Hospital, Dongfeng Motor Corporation and Hubei University of Medicine. | Shiyan, Hubei, China | Not Yet Recruiting |
| Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | Wuhan, Hubei, China | Recruiting |
| Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Shanxi Medical University | Taiyuan, Shanxi, China | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07333495