Condition: Sleep Apnea · Obstructive Sleep Apnea · Sponsor: Yale University
The study design is a randomized, controlled clinical trial to test the hypothesis that arousal threshold (ArTH) will affect how individuals with obstructive sleep apnea (OSA, Apnea-Hypopnea Index (AHI) of 10/hour of higher) respond to CPAP therapy regarding adherence and cognitive function (executive function). Investigators hypothesize that raising ArTH with eszopiclone will improve adherence to CPAP and neurocognitive function with CPAP therapy. Investigators also hypothesize that a lower baseline ArTH is associated with worse CPAP adherence, while a higher baseline ArTH is associated with improved neurocognitive outcomes with CPAP therapy.
This description comes directly from the study's public registry record.
Andrey Zinchuk, MD, MHS · 475-655-6199 · andrey.zinchuk@yale.edu
Iouri Kreinin, MD · iouri.kreinin@yale.edu
Always discuss trial participation with your own doctor first.
| Yale Centers for Sleep Medicine | North Haven, Connecticut, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07332442