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Study identifier: NCT07332234 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies

Condition: Meningitis · Meningitis/Encephalitis · Stroke  ·  Sponsor: Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.

This description comes directly from the study's public registry record.

Talk to the study team

Bogdan Pavel, MD, PhD, DESA  ·  +40726116536  ·  bogdan.pavel@umfcd.ro

Sebastian Isac, MD, PhD, DESA  ·  +40744543736  ·  sebastian.isac@umfcd.ro

Always discuss trial participation with your own doctor first.

Locations (2)

Fundeni Clinical InstituteBucharest, Bucharest, RomaniaRecruiting
"Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical DiseasesBucharest, Bucharest, RomaniaRecruiting

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Source record: clinicaltrials.gov/study/NCT07332234