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Study identifier: NCT07332091 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

Condition: Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis  ·  Sponsor: CSL Behring

PhasePhase 2
Planned participants84
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-related hereditary hemochromatosis (HFE-HH). The primary objective of the study is to assess the effect of vamifeport treatment on magnetic resonance imaging (MRI)-based liver iron concentration (LIC) in adult participants with HFE-HH.

This description comes directly from the study's public registry record.

Talk to the study team

Trial Registration Coordinator  ·  +16108784697  ·  clinicaltrials@cslbehring.com

Always discuss trial participation with your own doctor first.

Locations (99)

Banner MD AndersonGilbert, Arizona, United StatesNot Yet Recruiting
Infinity Clinical TrialsSan Diego, California, United StatesNot Yet Recruiting
Medical Oncology Associates of San DiegoSan Diego, California, United StatesNot Yet Recruiting
Green Leaf Clinical TrialsJacksonville, Florida, United StatesRecruiting
Indiana University Health University HospitalIndianapolis, Indiana, United StatesRecruiting
Ochsner Medical Complex - High GroveBaton Rouge, Louisiana, United StatesRecruiting
Johns Hopkins University School of MedicineBaltimore, Maryland, United StatesNot Yet Recruiting
American Oncology Partners, PA dba The Center for Cancer and Blood DisordersBethesda, Maryland, United StatesRecruiting
James M. Stockman Cancer InstituteFrederick, Maryland, United StatesRecruiting
University of Michigan Health System (UMHS)Ann Arbor, Michigan, United StatesNot Yet Recruiting
Aspirus St. Luke's Clinic - Duluth - Oncology & HematologyDuluth, Minnesota, United StatesRecruiting
Hunterdon Hematology Oncology, LLCFlemington, New Jersey, United StatesNot Yet Recruiting

+ 87 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07332091