Condition: Oral Leukoplakia · Sponsor: Alexandria University
Oral leukoplakia (OL) is recognized as the most common potentially malignant disorder of the oral mucosa. The pathogenesis of OL is complex and multifactorial, with oxidative stress playing a central role. Topical antioxidants have gained attention as therapeutic options to help stabilize lesions and potentially prevent malignant transformation. Both CoQ10 and curcumin have demonstrated a clinical success as strong antioxidants showing their capacity to reduce the lesion size and to stabilize the disease, ultimately preventing progression into oral malignancy. Aim: This study aims to clinically and biochemically assess the effectiveness of topical Coenzyme Q10 and Curcumin in the management of homogeneous oral leukoplakia.
This description comes directly from the study's public registry record.
Tasnim Saleem, BDS · 010 28946295 · tasneemsleem63@gmail.com
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| Outpatient Clinic of Oral medicine Department, Faculty of Dentistry, Alexandria University, Egypt | Alexandria, Egypt | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07331935