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Study identifier: NCT07328191 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Quality of Life-Guided Transfusion in Refractory MDS or AML

Condition: MDS · AML, Adult · Anemia  ·  Sponsor: Centre Hospitalier Universitaire de Nice

PhaseNA
Planned participants52
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients with refractory myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) in exclusive palliative care frequently receive red blood cell transfusions based on hemoglobin thresholds, despite limited evidence of clinical benefit in this setting. This prospective randomized study compares a standard hemoglobin-based transfusion strategy to a quality-of-life-guided strategy using the EQ-5D-5L questionnaire, with the aim of reducing transfusion burden while maintaining patient safety and quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Cluzeau, Professor  ·  0492039025  ·  cluzeau.t@chu-nice.fr

Lydia Cherfaoui  ·  0492039025  ·  cherfaoui.l@chu-nice.fr

Always discuss trial participation with your own doctor first.

Locations (1)

CHU de NiceNice, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07328191