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Study identifier: NCT07327931 Synced from ClinicalTrials.gov · July 28, 2026
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PENG Block Variants With Dexamethasone and Dexmedetomidine in Older Adults

Condition: Hip Osteoarthritis · Hip Pain Chronic  ·  Sponsor: Poznan University of Medical Sciences

PhaseNA
Planned participants120
Who can joinAll sexes, 65 Years to 100 Years
Healthy volunteersNo

About this study

This study will compare three different versions of the Pericapsular Nerve Group (PENG) block in adults aged 65 years and older who are undergoing surgery for hip conditions. The PENG block is a regional anesthesia technique that can reduce pain after surgery and decrease the need for strong opioid pain medications. All patients in the study will receive the PENG block with 20 mL of 0.2% ropivacaine, but they will be divided into three groups based on the additional medications used: Group 1: PENG block with ropivacaine plus 4 mg of dexamethasone given intravenously. Group 2: PENG block with ropivacaine plus 25 micrograms of dexmedetomidine given near the nerves and 4 mg of dexamethasone given intravenously. Group 3: PENG block with ropivacaine plus 25 micrograms of dexmedetomidine and 4 mg of dexamethasone given near the nerves. Both dexmedetomidine and dexamethasone are medications that may improve the strength and duration of nerve blocks. The main goal of this study is to determine which combination provides the best pain control after hip surgery, reduces the need for opioid medications, and improves patient comfort and recovery. We also aim to evaluate the safety and side-effects of each technique. We hypothesize that adding both dexmedetomidine and dexamethasone near the nerves will provide the longest and most effective pain relief when compared to intravenous administration alone. This trial may help identify the most effective PENG block formula for older ad…

This description comes directly from the study's public registry record.

Talk to the study team

Malgorzata Reysner, MD PhD  ·  +48 61 873 83 03  ·  mreysner@ump.edu.pl

Mslgorzata Reysner, MD PhD  ·  +48 61 873 83 03  ·  mreysner@ump.edu.pl

Always discuss trial participation with your own doctor first.

Locations (1)

Poznan University of Medical SciencesPoznan, PolandRecruiting

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Source record: clinicaltrials.gov/study/NCT07327931