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Study identifier: NCT07326943 Synced from ClinicalTrials.gov · July 28, 2026
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Minimum Effective Dose of Ropivacaine for Ultrasound-guided Interscalene Block

Condition: Hand and Forearm Trauma · Hand and Forearm Diseases  ·  Sponsor: Huazhong University of Science and Technology

PhaseNA
Planned participants56
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

Inter muscular groove brachial plexus block is a commonly used peripheral nerve block technique in clinical practice, commonly used for anesthesia and analgesia in clavicle, shoulder, and humeral surgeries. The classic ultrasound-guided intermuscular groove block also involves puncturing the needle to the level of the C5/C6 anterior branch for drug injection. After injection, local anesthetics mainly wrap around C5, C6, and some C7 nerve roots. Therefore, intermuscular groove block is mainly used for shoulder, humerus, and clavicle surgery. Due to incomplete ulnar block, it is not recommended for surgery on the elbow joint and its distal end.Scholars have found that using C5 as the puncture target to implement intermuscular groove block and administering 10ml of 0.75% ropivacaine, the success rate of ulnar nerve block is 19%. The success rate of ulnar nerve block with C6 as the puncture target was 93% when 10ml of 0.75% ropivacaine was administered. This suggests that blockade methods closer to the tail muscle groove on the tail side have a higher success rate for blocking the C7, C8, and T1 nerve roots. In our clinical work, the investigators found that when performing intermuscular groove block with C7 nerve root as the puncture target, local anesthetics not only stably wrap around C7 nerve root, but also spread to wrap around C5 and C6 nerve roots on the head side, and spread to the deep surface of the brachial plexus trunk on the tail side. Local anesthetic diffusion can …

This description comes directly from the study's public registry record.

Talk to the study team

Huailiang LI,  ·  86+18834183517  ·  574199674@qq.com

Zheng Hua, Study Principal Investigator  ·  86+18672750530

Always discuss trial participation with your own doctor first.

Locations (1)

Shanxi Bethune HospitalTaiyuan, Shanxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07326943