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Study identifier: NCT07326215 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+

Condition: Acute Respiratory Distress Syndrome · Acute Kidney Injury  ·  Sponsor: Vantive Health LLC

PhaseNA
Planned participants99
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

PrismaLung+ is a sterile, single-use medical device aimed at performing partial removal of carbon dioxide (CO2) from the patient's venous blood via diffusion through a membrane. The goal of this prospective, open label, randomized controlled study is to evaluate the efficacy and safety of PrismaLung+ on extracorporeal carbon dioxide removal (ECCO2R) in critically ill patients under invasive mechanical ventilation (IMV). Patients will be randomized to receive either IMV combined with ECCO2R (using PrismaLung+) in the study group or IMV alone in the control group, at a ratio of 2:1.

This description comes directly from the study's public registry record.

Talk to the study team

Global CORP Clinical Trials Disclosure  ·  +1 2249484283  ·  Global.CORP.ClinicalTrialsDisclosure@vantive.com

Always discuss trial participation with your own doctor first.

Locations (10)

China-Japan Friendship HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaNot Yet Recruiting
The University of Hong Kong-Shenzhen HospitalShenzhen, Guangdong, ChinaNot Yet Recruiting
The First Affiliated Hospital of Harbin Medical UniversityHarbin, Heilongjiang, ChinaNot Yet Recruiting
Zhongda Hospital Southeast UniversityNanjing, Jiangsu, ChinaNot Yet Recruiting
The First Affiliated Hospital of Nanchang UniversityNanchang, Jiangxi, ChinaNot Yet Recruiting
ZhongShan Hospital Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting
Sichuan Provincial People's HospitalChengdu, Sichuan, ChinaNot Yet Recruiting
The First Affiliated Hospital Zhejiang University School of MedicineHangzhou, Zhejiang, ChinaNot Yet Recruiting
Sir Run Run Shaw Hospital Zhejiang University School of MedicineHangzhou, Zhejiang, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07326215