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Study identifier: NCT07323420 Synced from ClinicalTrials.gov · July 29, 2026
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Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients

Condition: Respiratory Function · Pediatric Anesthesia · General Anesthesia  ·  Sponsor: Kırıkkale University

PhaseN/A
Planned participants75
Who can joinAll sexes, 2 Years to 12 Years
Healthy volunteersYes

About this study

This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia. Due to behavioral challenges, dental phobia, or medical conditions, general anesthesia is often required to ensure immobility and cooperation during dental treatments in children. In the clinic where the study will be conducted, the I:E ratio is routinely adjusted approximately 20-30 minutes before the end of the procedure to facilitate a smoother transition to spontaneous breathing during emergence from anesthesia. While 1:2 is commonly used, the 1:3 ratio may improve respiratory efficiency and recovery by prolonging the expiratory phase. The study aims to compare vital signs, respiratory parameters (heart rate, blood pressure, SpO₂, EtCO₂, respiratory rate), recovery quality, and respiratory complications between the two I:E ratios. The findings aim to optimize ventilation strategies and improve patient comfort and safety during emergence from anesthesia.

This description comes directly from the study's public registry record.

Talk to the study team

Gözde Nur Erkan Assisstant Professor  ·  +903182244927  ·  dr.gozdenur@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Kırıkkale University, Faculty of DentistryKirikkale, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07323420