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Study identifier: NCT07323355 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Single- vs Double-Layer Cesarean Scar Repair and Myometrial Thickness

Condition: Caesarean Section · Cesarean Scar Closure · Cesarean Scar Defect (Isthmococele)  ·  Sponsor: Ankara City Hospital Bilkent

PhaseNA
Planned participants102
Who can joinFemale, 18 Years to 44 Years
Healthy volunteersYes

About this study

Cesarean delivery (CD) is one of the most commonly performed surgical procedures worldwide, with a rising incidence particularly in high-income countries. Although often life-saving, cesarean delivery carries both short- and long-term maternal risks. Early complications include infection, hemorrhage, and thromboembolism, while inadequate uterine healing can lead to future complications such as uterine rupture and placenta accreta spectrum disorders. Additionally, cesarean scars may result in pregnancy complications, isthmocele formation, postmenstrual bleeding, pelvic pain, and dysmenorrhea. This highlights the need for optimization of the surgical technique. Despite increasing cesarean rates, there is no consensus on the optimal uterine closure method. Techniques vary in terms of the number of layers, suture locking style, and inclusion of the endometrium, and their comparative effectiveness in reducing scar defects remains unclear. Some previous studies have reported increased uterine rupture risk with single-layer locked sutures and better healing with double-layer closure, while others found no significant difference in scar outcomes. This study aims to investigate the effects of single- versus double-layer cesarean scar closure on myometrial thickness and its clinical implications.

This description comes directly from the study's public registry record.

Talk to the study team

Merve Didem Eşkin Tanrıverdi, MD  ·  +905354071467  ·  mrvddm@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ankara Bilkent City HospitalAnkara, Not Valid, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07323355