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Study identifier: NCT07323056 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Sacituzumab Tirumotecan and Limertinib for Potentially Resectable Stage Ⅲ EGFR-mutant Non-small Cell Lung Cancer

Condition: EGFR-mutant Non-small Cell Lung Cancer · Potentially Resectable  ·  Sponsor: Shanghai Pulmonary Hospital, Shanghai, China

PhasePhase 2
Planned participants36
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a prospective, single-arm, exploratory clinical research aimed at evaluating the efficacy and safety of lucetamab in combination with leucovorin in the conversion therapy of locally advanced potentially resectable EGFR mutation-positive non-small cell lung cancer, providing more robust clinical evidence for the improvement of treatment modalities for EGFR-mutated locally advanced NSCLC. At the same time, it seeks to identify biomarkers that can predict the therapeutic effect of the combination of lucetamab and leucovorin, offering more precise guidance for the selection of clinical treatment plans and enabling patients to receive the optimal treatment regimen.

This description comes directly from the study's public registry record.

Talk to the study team

Peng Zhang, PhD  ·  021-65115006  ·  zhangpeng1121@tongji.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Pulmonary HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07323056