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Study identifier: NCT07322783 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Osimertinib Combined With Savolitinib in the Treatment of NSCLC With Low Copy Number MET Amplification

Condition: EGFR Positive Non-small Cell Lung Cancer · MET Amplification  ·  Sponsor: Qingdao Central Hospital

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Osimertinib combined with savolitinib in the treatment of EGFR mutated osimertinib resistant NSCLC with low copy number MET amplification There are unmet medical needs in patients who resist to to osimertinib; savolitinib plus osimertinib shows high response rate and prolong progression-free survival in high copy number MET amplification patients. This study is to explore the efficacy and safety of the combination of savolitinib and osimertinib in osimertinb resistant patients with low copy number MET amplification.

This description comes directly from the study's public registry record.

Talk to the study team

youxin Ji, md, phD  ·  1718865657  ·  kevinji78@yahoo.com

keke nie  ·  8618561857907  ·  niekeke@uor.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Qingdao Central HospitalQingdao, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07322783