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Study identifier: NCT07322302 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs)

Condition: Trachoma · Eye Diseases · Trichiasis  ·  Sponsor: University of North Carolina, Chapel Hill

PhaseNA
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of this randomized clinical trial is to determine whether repeat trichiasis surgery performed with Bevel-Rotate Advancement Procedure (B-RAP) improves surgical success compared to Bilamellar Tarsal Rotation (BLTR) among a group of 8-10 TT surgeons in Tanzania. The study aims to enroll 1,000 individuals with PTT. The primary outcome is repeat PTT within one year after surgery. Additionally, the study will assess eyelid contour abnormalities and how they change over a two-year period as well as patient reported outcomes. If this project is successful in improving surgical outcomes, it could change the approach to treating PTT globally. Individuals with trichiasis have a significantly reduced quality of life; correcting their trichiasis long-term has the potential to improve their quality of life and their family members' quality of life considerably.

This description comes directly from the study's public registry record.

Talk to the study team

Emily Gower, PhD  ·  919 966 1420  ·  egower@unc.edu

Jerusha Weaver, MPH  ·  919 966 3527  ·  jweave25@unc.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of North CarolinaChapel Hill, North Carolina, United StatesRecruiting
Kongwa Trachoma ProjectMtwara, TanzaniaRecruiting

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Source record: clinicaltrials.gov/study/NCT07322302