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Study identifier: NCT07322003 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

Condition: Amyotrophic Lateral Sclerosis  ·  Sponsor: Prilenia

PhasePhase 3
Planned participants500
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if the drug pridopidine works to treat amyotrophic lateral sclerosis in adults. It will also help to learn about the safety of pridopidine. The main question it aims to answer is: Does pridopidine slow disease progression of ALS? Researchers will compare pridopidine to a placebo (a look-alike substance that contains no drug) to see if pridopidine works to treat ALS. Participants will: Take pridopidine or a placebo by mouth every day for 48 weeks. Afterwards, all participants will take pridopidine for another 48 weeks. Visit the clinic once every 1-3 months for checkups and tests

This description comes directly from the study's public registry record.

Talk to the study team

Prilenia Medical Information  ·  857-574-5755  ·  MedInfo@prilenia.com

Always discuss trial participation with your own doctor first.

Locations (47)

Barrow Neurological InstitutePhoenix, Arizona, United StatesRecruiting
California Pacific Medical CenterSan Francisco, California, United StatesRecruiting
University of Colorado CU Anschutz NeurologyAurora, Colorado, United StatesRecruiting
Mayo ClinicJacksonville, Florida, United StatesRecruiting
University of South FloridaTampa, Florida, United StatesRecruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
University of KansasFairway, Kansas, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Sean M. Healey & AMG Center for ALSBoston, Massachusetts, United StatesRecruiting
Washington UniversitySt Louis, Missouri, United StatesRecruiting
Somnos Clinical ResearchLincoln, Nebraska, United StatesRecruiting

+ 35 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07322003