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Study identifier: NCT07321704 Synced from ClinicalTrials.gov · July 28, 2026
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Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease

Condition: Pilonidal Disease  ·  Sponsor: Yosef Nasseri, MD

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Pilonidal disease is a chronic condition that causes painful inflammation and infection near the top of the buttocks. Many patients require surgery, and one commonly used approach is a bilateral gluteal fasciocutaneous flap with midline closure along with placement of an extracellular matrix to support wound healing. Although effective, this surgery can still lead to wound problems such as infection, fluid collection (seroma), wound separation (dehiscence), and delayed healing. This study aims to compare two different solutions used to rinse the surgical wound before closing it. One solution is Irrisept, which contains 0.05% chlorhexidine gluconate, an antiseptic designed to reduce bacteria. The other is normal saline, which is the current standard rinse used in surgery. The goal is to determine whether using Irrisept can safely reduce post-operative infections and wound-related complications in patients undergoing flap closure and extracellular matrix implantation for pilonidal disease.

This description comes directly from the study's public registry record.

Talk to the study team

Yosef Nasseri, MD  ·  310-289-1518  ·  yosefn@surgerygroupofla.com

Always discuss trial participation with your own doctor first.

Locations (1)

Surgery Group LALos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07321704