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Study identifier: NCT07320924 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Patient-specific Reconstruction Plate for Segmental Mandibular Defects

Condition: Mandibular Resection · Mandibular Reconstruction* / Methods · Mandibular Reconstruction  ·  Sponsor: Alexandria University

PhaseNA
Planned participants14
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require extensive intraoperative bending, often resulting in imperfect adaptation, press-to-contact fixation, and residual stresses that increase the risk of hardware fatigue and fracture. Recent advances in computer-aided design and manufacturing (CAD/CAM) and virtual surgical planning (VSP) have improved precision in maxillofacial reconstruction. Patient-Specific Reconstruction Plates (PSRP), developed from virtual planning and patient-specific anatomical data, offer a bespoke contour adaptation, predictable screw positioning, and elimination of press-fit deformation. This customization improves alignment, mechanical stability, and long-term outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

yehia A El-Mahallawy., PhD  ·  +201007217014.  ·  yehia.el-mahallawy@alexu.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

Faculty of Dentistry, Alexandria UniversityAlexandria, Alexandria Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07320924