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Study identifier: NCT07319780 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias

Condition: Distal Hypospadias · Hypospadias  ·  Sponsor: National Children's Medical Center, Uzbekistan

PhaseNA
Planned participants100
Who can joinMale, 6 Months to 84 Months
Healthy volunteersNo

About this study

Hypospadias is a common congenital condition in boys in which the opening of the urethra is located on the underside of the penis. Distal hypospadias is the most common form and is usually treated surgically using tubularized incised plate (TIP) urethroplasty. In boys with an unfavorable urethral plate, graft-augmented techniques (G-TIP) are often used; however, postoperative complications such as urethrocutaneous fistula and narrowing of the urethral opening (meatal stenosis) may still occur. Platelet-rich fibrin (PRF) is a biological material obtained from the patient's own blood that contains natural growth factors and may help improve tissue healing. This study aims to evaluate whether the use of PRF during surgery can reduce postoperative complications and improve surgical outcomes in children undergoing hypospadias repair.

This description comes directly from the study's public registry record.

Talk to the study team

Zafar Abdullaev, MD PhD  ·  +998-90-909-9911  ·  Abdullaev.med@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Dr. Cipto Mangunkusumo HospitalJakarta, DKI Jakarta, IndonesiaNot Yet Recruiting
National Children's Medical CenterTashkent, Tashkent, UzbekistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07319780