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Study identifier: NCT07319078 Synced from ClinicalTrials.gov · July 29, 2026
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Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction

Condition: Irritable Bowel Disease · Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS) · Functional Dyspepsia  ·  Sponsor: Karolinska Institutet

PhaseNA
Planned participants200
Who can joinAll sexes, 8 Years to 17 Years
Healthy volunteersNo

About this study

Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional dyspepsia. These conditions are caused by disrupted communication between the brain and the gut. They are linked to significant suffering, reduced quality of life, and higher school absenteeism. Psychological treatments such as cognitive behavioral therapy (CBT) have shown good effect, but waiting times within healthcare are often long. Therefore, there is a need for more accessible and cost-effective treatment alternatives. The goal of this clinical trial is to explore whether gut-directed hypnotherapy, already used successfully in the Netherlands, can be implemented as a new treatment option in Swedish healthcare. In addition, the study will compare gut-directed hypnotherapy with internet-based CBT (iCBT) to learn which digital treatment works best for children and adolescents with DGBI. Participants will: Be children or adolescents between 8 and 17 years old. First take part in a 4-week online education program called the "gut-school," which explains the stomach, the brain, and how symptoms can be managed. If symptoms remain after the gut-school, be randomly assigned to one of two digital treatments: iCBT (internet-based cognitive behavioral therapy). 10 week long. Gut-directed hypnotherapy, delivered as audio recordings to be used at home. …

This description comes directly from the study's public registry record.

Talk to the study team

Tea Soini, MD PhD  ·  +46 766457611  ·  tea.soini@ki.se

Frida Andersson, MSc  ·  forskningsprojekt-pippi@ki.se

Always discuss trial participation with your own doctor first.

Locations (1)

Sachs Children's HospitalStockholm, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07319078