Condition: Advanced Breast Cancer · Metastatic Breast Cancer (HR+/ HER2-) · Colorectal Cancer · Sponsor: Pfizer
The purpose of this study is to learn about the safety and effects of the study medicine when given alone or together with other anti-cancer therapies. Anti-cancer therapy is a type of treatment to stop the growth of cancer. This study also aims to find the best amount of study medication. This study is seeking participants that have advanced or metastatic breast cancer (BC), or advanced or metastatic colorectal cancer (CRC). All participants in this study will take the study medication (PF-08032562) as pill by mouth. This will be repeated for 28-day cycles. Depending on which part of the study participants are enrolled into, they will receive the study medication PF-08032562 alone or in combination with other anti-cancer medications. The study medication (PF-08032562) will be taken by mouth (PO) in combination with other anti-cancer medications given in the study clinic by intramuscular (IM) injection into the muscle or intravenous (IV) infusion that is directly injected into the veins at different times (depending on the treatment) during the 28-day cycle. The study may also test different schedules.
This description comes directly from the study's public registry record.
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Always discuss trial participation with your own doctor first.
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Duarte, California, United States | Recruiting |
| START Midwest, LLC | Grand Rapids, Michigan, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center - Investigational Drug Service Pharmacy | Long Island City, New York, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street). | New York, New York, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center 53rd street. | New York, New York, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center - Main Campus | New York, New York, United States | Recruiting |
| The University of Texas MD Anderson Cancer Center - Conroe | Conroe, Texas, United States | Recruiting |
| The University of Texas - M.D. Anderson Cancer Center | Houston, Texas, United States | Recruiting |
| The University of Texas, MD Anderson Cancer Center - West Houston | Houston, Texas, United States | Recruiting |
| The University of Texas, MD Anderson Cancer Center - League City | League City, Texas, United States | Recruiting |
| START San Antonio | San Antonio, Texas, United States | Recruiting |
| The University of Texas, MD Anderson Cancer Center - Sugar Land | Sugar Land, Texas, United States | Recruiting |
+ 1 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07318805