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Study identifier: NCT07318519 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)

Condition: Cancer · Cancer Pain · Chronic Cancer Pain  ·  Sponsor: Medstar Health Research Institute

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

While chronic cancer pain affecting as many as 75% of patients is typically addressed using pharmacologic interventions, experts and patients alike support maximizing any relevant non-pharmacologic interventions as well, such as cognitive behavioral therapy. Virtual reality, a novel technology that can temporarily immerse users in a calm, pleasant environment, has been increasingly shown to facilitate improvement in different acute and chronic pain syndromes by providing distraction from pain and lowering pain sensation. To address the significant needs of patients living with chronic cancer pain, we aim to develop and pilot test a prototype device that will leverage cognitive behavioral therapy principles to deliver a novel virtual reality pain therapy. The investigators will do this through the following steps: Step 1. Develop and refine a CBT-assisted VR prototype for patients with chronic cancer pain (VR-CAN). Step 2. Conduct a randomized controlled trial to examine the feasibility, acceptability, usability, safety, and initial clinical impact of the developed VR-CAN prototype compared to a tablet-based two-dimensional video control group. Step 3. Collect and evaluate qualitative post-intervention data on VR-CAN participants' preferences, thoughts, and feelings about the VR-CAN technology and protocol to optimize for a future, larger, fully powered randomized controlled trial.

This description comes directly from the study's public registry record.

Talk to the study team

Hunter Groninger, MD  ·  202-877-7445  ·  hunter.groninger@medstar.net

Always discuss trial participation with your own doctor first.

Locations (2)

MedStar Health Research InstituteWashington D.C., District of Columbia, United StatesRecruiting
Duke University School of MedicineDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07318519