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Study identifier: NCT07317934 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy and Safety of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (STELLAR)

Condition: Neovascular Age-Related Macular Degeneration (nAMD) · Wet AMD  ·  Sponsor: Innostellar Biotherapeutics Co.,Ltd

PhasePhase 3
Planned participants332
Who can joinAll sexes, 50 Years to 80 Years
Healthy volunteersNo

About this study

This is a Phase III, randomized, open-label, active-controlled study to evaluate the efficacy and safety of subretinal injection of LX102 in participants with neovascular age-related macular degeneration. The study will evaluate a single subretinal injection of LX102 compared to an active comparator. The primary endpoint of this study is the mean change from D0 in BCVA based on an average at weeks 40 and 48.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (31)

The First Affiliated Hospital of University of Science and Technology of ChinaHefei, Anhui, ChinaNot Yet Recruiting
Beijing HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Peking Union Medical College HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
The Second Affiliated Hospital of Chongqing Medical UniversityChongqing, Chongqing Municipality, ChinaNot Yet Recruiting
The First Affiliated Hospital of Jinan UniversityGuangzhou, Guangdong, ChinaNot Yet Recruiting
Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong KongShantou, Guangdong, ChinaNot Yet Recruiting
Zhongshan Ophthalmic Center, Sun Yat-sen UniversityZhongshan, Guangdong, ChinaNot Yet Recruiting
The Second Affiliated Hospital of Harbin Medical UniversityHarbin, Heilongjiang, ChinaNot Yet Recruiting
Central Theater Command General Hospital of PLAWuhan, Hubei, ChinaNot Yet Recruiting
The Second Xiangya Hospital, Central South UniversityChangsha, Hunan, ChinaNot Yet Recruiting
Aier Eye Hospital Group Co., LTD. Changsha Aier Eye HospitalChangsha, Hunan, ChinaNot Yet Recruiting
The Affiliated Eye Hospital of Nanjing Medical UniversityNanjing, Jiangsu, ChinaNot Yet Recruiting

+ 19 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07317934