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Study identifier: NCT07317310 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The NTU JO-SMART Study

Condition: Knee Osteoarthristis · Diabetes (DM) · Obesity & Overweight  ·  Sponsor: National Taiwan University Hospital

PhaseNA
Planned participants312
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study recruits patients with coexisting obesity and knee osteoarthritis (KOA) to implement the NTU-JO Smart Program, an innovative intervention integrating AI-assisted community-based exercise with continuous glucose monitoring (CGM). The primary objective is to investigate whether this intervention can improve glycemic control in this comorbid population. Other outcome measures include the risk of total knee arthroplasty (TKA), body weight changes, pain intensity scores, bone mineral density (BMD), cognitive function, as well as the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Patient-Reported Outcomes Measurement Information System (PROMIS) scores, which reflect the patients' overall functional status. The project also sought to explore the long-term association of the NTU-JO Smart Program with the development of type 2 diabetes (T2D) and major renal events, thereby facilitating patient-centered early treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Chien-Hsieh Chiang, MD, MPH, PhD  ·  +886-2-23123456  ·  jiansie@gmail.com

Shengyong Tang, MD  ·  +886-928436686  ·  tangsam0627@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

National Taiwan University HospitalTaipei, Taiwan, TaiwanRecruiting
National Taiwan University Hospital Yunlin BranchYunlin, Taiwan, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT07317310