Condition: Hernia · Hernia, Ventral · Hernia Incisional · Sponsor: Umeå University
The study is a multicentre, single-blinded, randomised controlled trial. Ventral hernia patients with an aperture width between four and eight centimetres are randomised to either participation in a multimodal preoptimisation programme, including interventions to increase physical activity, promote weight loss, and optimise the treatment of comorbidities, or to surgery without structured preoptimisation. The primary endpoint is complications at three months postoperatively. During surgery, biopsies of skin, muscle, and fascia will be collected, along with pre- and postoperative blood samples, to analyse the molecular effects of preoptimisation, particularly in relation to collagen metabolism.
This description comes directly from the study's public registry record.
Gunnar Nordqvist, M.D. · +46768227094 · gunnar.nordqvist@umu.se
Viktor Holmdahl, Phd · viktor.holmdahl@umu.se
Always discuss trial participation with your own doctor first.
| Gällivare hospital | Gällivare, Norrbotten County, Sweden | Recruiting |
| Sunderby Hospital | Luleå, Norrbotten County, Sweden | Recruiting |
| Lycksele Hospital | Lycksele, Västerbotten County, Sweden | Not Yet Recruiting |
| Skellefteå Hospital | Skellefteå, Västerbotten County, Sweden | Not Yet Recruiting |
| Umeå University Hospital | Umeå, Västerbotten County, Sweden | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07316426