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Study identifier: NCT07315828 Synced from ClinicalTrials.gov · July 28, 2026
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Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Giant Cell Tumor of Bone Surgery

Condition: Giant Cell Tumor of Bone  ·  Sponsor: Shanghai Jiao Tong University Affiliated Sixth People's Hospital

PhasePhase 4
Planned participants40
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study evaluates the diagnostic accuracy of Indocyanine Green (ICG) fluorescence imaging in visualizing residual lesions of Giant Cell Tumor of Bone (GCTB) in the tumor cavity during surgery. Patients diagnosed with GCTB will receive an intravenous injection of ICG prior to the operation to label tumor tissues. During the procedure, surgeons will use a near-infrared fluorescence imaging system to visualize the tumor cavity and identify potential residual lesions after standard curettage. The study aims to determine the sensitivity, specificity, positive predictive value, and negative predictive value of ICG fluorescence imaging by comparing the intraoperative fluorescence findings with the final pathological results of the validation samples.

This description comes directly from the study's public registry record.

Talk to the study team

Qingcheng Yang, Prof.  ·  +86 21 6431 9181  ·  tjyqc@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Sixth People's HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07315828