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Study identifier: NCT07315360 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function

Condition: Renal Impairment · Healthy  ·  Sponsor: Pfizer

PhasePhase 1
Planned participants28
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

The purpose of this study is to learn how the study medicine PF-07328948 is processed by the body and how safe and tolerable it is in adults with different levels of kidney function. The study will include participants who: * Are aged 18 to 80 years. * Either have normal kidney function or long-term reduced kidney function (moderate or severe). * Have a BMI (body mass index) of 17.5 to 40 kilogram per meter squared, inclusive, and a total body weight of more than or equal to 45 kilograms or 99 pounds. All participants will receive a single dose of PF-07328948 as a tablet taken by mouth. Participants will stay at a clinical research unit for about 6 days to receive the study medicine and undergo safety checks. Total participation lasts up to 64 days, including screening, inpatient stay, and a follow-up call. The study is not randomized or blinded, meaning all participants and study staff know which treatment is being given. Group assignment is based on kidney function tests done during screening. The results will help researchers understand how reduced kidney function affects the way PF-07328948 works in the body.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (4)

Orange County Research CenterLake Forest, California, United StatesRecruiting
Orlando Clinical Research CenterOrlando, Florida, United StatesRecruiting
Genesis Clinical Research, LLCTampa, Florida, United StatesRecruiting
Nucleus NetworkSaint Paul, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07315360