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Study identifier: NCT07314606 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Combining Nutritional Therapy and Anti-TNFα Treatment in Pediatric Patients With Crohn's Disease

Condition: Crohn Disease (CD) · IBD (Inflammatory Bowel Disease) · IBD - Inflammatory Bowel Disease  ·  Sponsor: University of British Columbia

PhaseNA
Planned participants140
Who can joinAll sexes, 9 Years to 17 Years
Healthy volunteersNo

About this study

Children with Crohn's disease (CD), a type of Inflammatory Bowel Disease (IBD), often face serious health challenges, including poor growth, frequent hospital stays, and long-term medication use. Although biologic drugs like infliximab, an anti-TNFα (Tumor necrosis factor α) medication, have improved treatment, they don't work for everyone: many children still experience symptoms or disease flare-ups. Nutritional therapies, especially the Crohn's Disease Exclusion Diet (CDED), may help improve treatment outcomes. This study will assess whether starting CDED at the same time as infliximab leads to better responses to treatment. The goal of this study is to improve how well children respond to therapy, reduce drug exposure, and support better long-term health.

This description comes directly from the study's public registry record.

Talk to the study team

Kevan Jacobson, MBBCh, FRCP, FRCPC, AGAF, CAGF  ·  604-875-2332  ·  kjacobson@cw.bc.ca

Fanny Lemarie, MSc, PhD  ·  604-441-4992  ·  fanny.lemarie@ubc.ca

Always discuss trial participation with your own doctor first.

Locations (1)

The University of British ColumbiaVancouver, British Columbia, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07314606