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Study identifier: NCT07314450 Synced from ClinicalTrials.gov · July 28, 2026
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Procedural Sedation and Analgesia for Treatment of Adults With Fractures and Dislocations in the Emergency Department

Condition: Pain, Procedural · Analgesia · Extremity Injury  ·  Sponsor: Region Zealand

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to evaluate the effectiveness and safety of different procedural sedation and analgesia methods used for adults with painful fractures requiring reduction treatment in the emergency department. The main questions it aims to answer are: * Which sedation and analgesia methods provide the best patient satisfaction and pain relief? * How do different treatment methods affect clinician satisfaction and the occurrence of adverse events? The investigators will compare different types of procedural sedative and analgesic treatments (such as systemic sedation/analgesia and regional techniques like nerve or hematoma blocks) to see which approach offers the best patient satisfaction and most effective pain control. Participants will: Be adult patients with upper or lower extremity fractures or joint dislocations requiring painful reduction procedures. Receive one of the routinely used sedation or analgesia treatments (or no analgesia) during their emergency department care. Report their pain levels and satisfaction before, during, and after treatment. Be monitored for any side effects, complications, or use of antidotes. Data will be collected over a six-month period at Odense University Hospital, Holbæk Hospital, and Zealand University Hospital, Køge, following the STROBE guidelines for observational studies.

This description comes directly from the study's public registry record.

Talk to the study team

Sophie Sværke, MD  ·  31368854  ·  Ibes@regionsjaelland.dk

Ole Mathiesen, Professor  ·  Omat@regionsjaelland.dk

Always discuss trial participation with your own doctor first.

Locations (3)

Emergency Department, Holbæk HospitalHolbæk, Region Sjælland, DenmarkRecruiting
Emergency Department, Zealand University HospitalKøge, Region Sjælland, DenmarkRecruiting
Emergency Department, Odense University HospitalOdense, Region Syddanmark, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT07314450