Condition: Cystic Fibrosis (CF) · Mucoviscidosis · Sponsor: University Hospital, Lille
Cystic fibrosis is a genetic disorder affecting the entire body and associated with respiratory exacerbations, impaired quality of life and reduced life expectancy. The therapeutic management of cystic fibrosis has been profoundly changed by the recent arrival of a combination of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators, Elexacaftor-Tezacaftor-Ivacaftor (ETI), which improve quality of life, respiratory function and reducing the number of exacerbations. The impact of these treatments on exercise adaptation has not been clearly identified. The main objective is to estimate the prevalence of ventilatory reserve amputation during submaximal exercise testing assessed by the 6-minute walk test (6MWT) in patients with cystic fibrosis treated with ETIs.
This description comes directly from the study's public registry record.
Camille AUDOUSSET, Doctor · +33 3.20.44.41.45 · DRC@chu-lille.fr
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| University Hospital | Lille, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07314229