Condition: Acute Respiratory Syndrome Distress · Positive End-Expiratory Pressure · Electrical Impedance Tomography · Sponsor: Nguyen Dang Thu
Acute respiratory distress syndrome (ARDS) remains a serious and often fatal complication in patients following severe trauma or major surgery. Mechanical ventilation is essential for supportive care in this population, but may aggravate lung injury when suboptimal ventilatory settings are applied. Positive end-expiratory pressure (PEEP) is crucial for maintaining alveolar recruitment; however, optimal PEEP selection in trauma- or postoperative-associated ARDS remains uncertain. Electrical impedance tomography (EIT) enables bedside, real-time assessment of regional ventilation and may support optimal PEEP titration by balancing alveolar overdistension and collapse. This study compares EIT-guided PEEP optimization with the conventional low FiO₂-PEEP strategy in terms of oxygenation and respiratory mechanics in patients with moderate to severe ARDS following trauma or surgery.
This description comes directly from the study's public registry record.
Nguyen Viet Minh · (+84) 918292528 · vietminh1510@gmail.com
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| Center for Anesthesia and Surgical Intensive Care, Viet Duc University Hospital | Hanoi, Vietnam | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07313644